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仪器/ 产品中心/ 色谱柱/ 保护柱/ 保护柱套/ Dionex Acclaim Trinity P2 LC Column 液相色谱柱
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Dionex Acclaim Trinity P2 LC Column 液相色谱柱

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详细介绍

Acclaim Trinity P2 LC Column


The Thermo Scientific? Acclaim? Trinity? P2 column is a high-performance, silica-based column specifically designed for separation of pharmaceutical mono- and multi-valent counterions by high-performance liquid chromatography (HPLC). This column was engineered for analytical chemists who need simple, robust, fast, generic methods. The Acclaim Trinity P2 columns provide an effective solution for counterion analysis using one column and one method on a standard HPLC instrument.

? Desired selectivity for pharmaceutical mono- and multi-valent counterion screening
? Retention of ionic and ionizable analytes without using ion-pairing reagents
? Compatibility with charged aerosol and mass spectrometry detection methods
? Easy to use
? Rugged packing

The Acclaim Trinity P2 column is based on nanopolymer silica hybrid (NSH) technology.  It consists of high-purity, porous, 3 ?m particles coated with charged nanopolymer particles: the innerpore area of the silica particles is modified with a covalently bonded hydrophilic layer that provides cation exchange retention, while the outer surface is modified with anion-exchange nanopolymer beads. This chemistry design ensures spatial separation of the anion exchange and cation exchange regions. In addition, its hydrophilic surface makes it useful as a hydrophilic interaction liquid chromatography (HILIC) column. Thus, the Acclaim Trinity P2 column provides cation-exchange, anion-exchange, and HILIC retentions on the same stationary phase.

NSH Chromatographic Features

  • Multiple retention mechanisms including HILIC, anion-exchange, and cation-exchange
  • Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
  • Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
  • Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

技术参数:



Acclaim Trinity P2 Column – Superior Performance for Pharmaceutical Applications Specifications
Column chemistrySAX, WCX and HILIC Mixed-Mode
Operating pressure limit6000 psi
Operating pH range2.0 – 8.0
Operating flow rate range0.3 – 0.90 mL/min for 3.0-mm i.d. formats
0.15 – 0.45 mL/min for 2.1-mm i.d. formats
Organic compatibilityCompatible with most common HPLC organic solvents except for alcohols.
Aqueous compatibility0-100% aqueous phase
Storage solutionMeCN/10mM NH4OAc, pH5 v/v 90/10 or pure MeCN (acetonitrile)

订购信息:



Analytical Columns
Acclaim Trinity P2,3?m,Analytical column, 3.0 x 50mm085433
Acclaim Trinity P2,3?m,Analytical column, 3.0 x 100mm085434
Acclaim Trinity P2,3?m,Analytical column, 2.1 x 50mm085431
Acclaim Trinity P2,3?m, Analytical column, 2.1 x 100mm085432
Guard Columns
Acclaim Trinity P2,3?m,Guard column, 3.0 x 10mm, 2/pk; requires holder 069580085436
Acclaim Trinity P2,3?m,Guard column, 2.1 x 10mm, 2/pk; requires holder 069580085435
Acclaim SST Guard Cartridge Holder V-2069580
Acclaim Guard Kit (Holder and coupler) V-2069707
Guard to Analytical Column Coupler V-2074188


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