Rabbit Anti-Hepcidin-25

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RabbitAnti-Hepcidin-25Cat.Number:By-6372RQuantitysize:0.2ml（1mg/1ml,LyophilizedorLiquid.Buffer=Preservative:15mMSodiumAzide,Constituents:1%BSA,0.01MPBS,pH7.4.Reconstitutewith0.2mlsteriledistilledwater.）Background:Seemstoactasasigna领moleculeinvolvedinthemaintenanceofironhomeostasis.SeemstoberequiredinconjunctionwithHFEtoregulatebothintestinalironabsorptionandironstorageinmacrophages.HasstrongantimicrobialactivityagainstE.coliML35PN.cinereaandweakeragainstS.epidermidis,S.aureusandgroupbstreptococcusbacteria.ActiveagainstthefungusC.albicans.NoactivityagainstP.aeruginosa.Tissuespecificity:Highestexpressioninliverandtoalesserextentinheartandbrain.Lowlevelsinlung,tonsils,salivarygland,trachea,prostategland,adrenalglandandthyroidgland.Secretedintotheurine.Alsoknownas:Hamp;HEPC;HEPC_HUMAN;Hepc20;Hepc25;HEPCIDIN;Hepcidin20;Hepcidin25;Hepcidinantimicrobialpeptide;Hepcidin-20;Hepcidin25;HFE2;HFE2B;LEAP1;LEAP-1;LEAP1;Liverexpressedantimicrobialpeptide;Liver-expressedantimicrobialpeptide1;PLTR;Putativelivertumorregressor.Specificity:RabbitPolyclonalIgG,affinitypurifiedbyProteinA.Reactswith:hu,mo,ratImmunogen:KLHconjugatedsyntheticpeptidederivedfromhuHepcidin-25.Predictedmolecularweight:20-32kDaApplication:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500Notyettestedinotherapplications.Optimalworkingdilutionsmustbedeterminedbytheenduser.Storage:Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.TheLyophilizedorLiquidantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C.ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications
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