人毛发乳头细胞HHDPC

The dermal papillae are a highly active group of cells derived from the dermis mesenchyme. Located at the base of the hair follicles, the dermal papillae play a crucial role in hair growth cycle by inducing follicle development from the epidermis to produce hair fiber [1]. Hair growth is tightly regulated by the epithelial-mesenchymal interaction of hair follicular cells, which involves various molecular pathways including BMP and Wnt signa领 [2, 3]. A previous study showed that dermal papilla cells gradually lost their hair inductivity and proliferation capacity in long-term cultures [4]. Continuous advancement in culture techniques will help provide better models for studying hair biology and hair reconstitution in regenerative medicine.