仪器网

欢迎您: 免费注册 仪器双拼网址:www.yiqi.com
首页-资讯-资料-产品-求购-招标-品牌-展会-行业应用-社区-供应商手机版
官方微信
中国仪器网• 行业应用
应用首页 解决方案 行业标准
应用
  • 产品
  • 企业
  • 品牌
  • 资料
  • 问答
仪器网/ 行业应用/ 解决方案/ SFC VCD振动圆二色光谱仪测量蛋白质

SFC VCD振动圆二色光谱仪测量蛋白质

点击这里给我发消息
内容节点
概述
实验/设备条件
样品提取
实验/操作方法
实验结果/结论
仪器/耗材清单
It is generally understood that chiral compounds have different bioactivities depending upon the absolute
configuration of each compound. Some familiar examples include glutamic acid and thalidomide. Lglutamic
acid demonstrates the Umami taste*1, while D-glutamic acid has a bitter taste, similarly, the R
form of thalidomide is a sedative, but the S form has teratogenic activity. Thus, the separation and study
of chiral compounds is critical for many reasons.
The functionalities of chiral compounds have been studied for the development of advanced molecules
for many applications. The study of chiral compounds has spread to several fields such as natural
products, pharmaceuticals and other functional molecules, and it can be pointed out that among those
studies, the structural analysis of chiral compounds is a very important topic. X-ray Diffraction (XRD),
Nuclear Magnetic Resonance (NMR) and Electronic Circular Dichroism (ECD) using UV/Vis light are
employed as primary methods for the structural analysis of chiral compounds. In this paper, the
measurement of chiral compounds by Vibrational Circular Dichroism (VCD) using infrared light will be
outlined.
VCD is a method to measure the difference of absorbance intensity between left-hand and right-hand
circularly polarized light as shown in Figure 1. It is an advantage of VCD that this method can be applied
to almost all organic compounds in the same way as infrared (IR) spectroscopy. In addition, by
comparing the measurement results with calculated results by ab-initio molecular orbital calculations, the
absolute configuration of the sample can be determined. However, since the peak intensity of VCD
spectra are 1,000 10,000 times weaker than that of standard IR spectra, spectroscopic instruments
with high sensitivity and stability with very small baseline fluctuations are required. The FVS-6000 VCD
system has a high sensitivity detector, suitable optical JASCO振动圆二色光谱仪VCD FVS-6000
相关产品
相关解决方案
热门解决方案
最新解决方案
在线留言
关于我们 | 诚聘英才 | 客户投诉 | 本站服务 | 会员中心 | 买家中心
仪器网(www.yiqi.com) --专业分析仪器,检测仪器平台,实验室仪器设备交易网,仪器行业专业网络宣传推广媒体。
仪器网(www.yiqi.com)--仪器拼音域名网址,简单,易懂,好记,可信; 符合仪器用户的记忆和使用习惯,是仪器选型采购的专业平台。
销售电话: 400 822 6768 企业销售咨询: 021-68559399 021-68551566 VIP会员售后QQ: 83550177 VIP会员销售QQ: 65884322
网站售后: 021-50353779 综合业务QQ: 11694366 免费企业会员售后QQ: 932545765 展会合作QQ: 784540580 仪器求购QQ: 61224355
Copyright 2004-2024 www.yiqi.com All Rights Reserved. 沪ICP备16012899号 沪B220170422号 互联网药品信息服务资格证书 沪公网安备 31011502008050号

沪公网安备 31011502008050号


若仪器网内容侵犯到您的权益，请及时告诉我们,我们马上修改或删除。邮箱：hezou_yiqi@163.com
官方微信

仪器网微信服务号

扫码获取最新信息


仪器网官方订阅号

扫码获取最新信息

在线客服

咨询客服

在线客服
工作日:  9:00-18:00
联系客服 企业专属客服
电话客服:  400-822-6768
工作日:  9:00-18:00
订阅商机

仪采招微信公众号

采购信息一键获取海量商机轻松掌控