TNF alpha 抗体报价，说明书

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【导读】TNFalpha抗体报价，说明书 Rabbit Anti-TNFalpha抗体报价，说明书FROM:ABCAMCatalogNumber: Rs-0078R Q...

TNFalpha抗体报价，说明书

Rabbit Anti-TNFalpha抗体报价，说明书
FROM:ABCAM
CatalogNumber: Rs-0078R
Quantitysize: 0.1ml （dilutewithpH7.4 0.01MPBSorantibodydiluent）

Background: TumorNecrosisFactorAlpha（TNFalpha）isaproteinsecretedbylipopolysaccharidestimulatedmacrophages,andcausestumornecrosiswheninjectedintotumourbearingmice.TNFalphaisbelievedtomediatepathogenicshockandtissueinjuryassociatedwithendotoxemia.TNFalphaexistsasamultimeroftwo,three,orfivenoncovalentlylinkedunits,butshowsasingle17kDabandfollowingSDSPAGEundernonreducingconditions.TNFalphaiscloselyrelatedtothe25kDaproteinTumourNecrosisFactorbeta（lymphotoxin）,sharingthesamereceptorsandcellularactions.TNFalphacausescytolysisorcytostasisofcertaintransformedcells,beingsynergisticwithinterferongammainitscytotoxicity.Althoughithaslittleeffectonmanyculturednormalhumancells,TNFalphaappearstobedirectlytoxictovascularendothelialcells.OtheractionsofTNFalphaincludestimulatinggrowthofhumanfibroblastsandothercelllines,activatingpolymorphonuclearneutrophilsandosteoclasts,andinductionofinterleukin1,prostaglandinE2andcollagenaseproduction.TNFalphaiscurrentlybeingevaluatedintreatmentofcertaincancersandAIDSRelatedComplex.

pecificity:
– Anti-TNFalphaisarabbitpolyclonalantibodyunconjugated
– specificforTNFalphaofhu,mo
– useforwesternblotting,elisa,immunoprecipitationandimmunohistochemistry
– ProteinGaffinitychromatographypurification,purity:>95%
– Isotype: IgG
– molwt: 17/26kDa

Application:
– Westernblotting1:100-500
– Immunohistochemistry1:100-500
– ELISA1:500-1000
– Optimalworkingdilutionsmust bedeterminedbytheenduser.

Storage: Storeat-20℃foroneyear.Avoidrepeatedfreeze/thawcycles.The lyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreater thanayearwhenkeptat-20℃.WhenreconstitutedinsterilepH7.40.01MPBSordiluent ofantibody,theantibodyisstableforatleastsixweeksat2-4℃

ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforusein human,therapeuticordiagnosticapplications.
Rabbit Anti-TNFalpha抗体报价，说明书

2004-07-13 09:31:27

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