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Recombinant Human DKK-1 Protein, His Tag 重组人DKK-1蛋白

品牌：翌圣生物
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供应商报价：面议

翌圣生物科技(上海)股份有限公司更新时间：2024-12-24 09:03:45

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产品信息

产品名称	产品编号	规格
Recombinant Human DKK-1 Protein, His Tag	92275ES25	25 μg
	92275ES60	100 μg
	92275ES76	500 μg

产品描述

Dickkopf related protein 1 (Dkk-1) is the founding member of the Dickkopf family of proteins that includes Dkk-1, -2, -3, -4, and a related protein. Dkk antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes.

性能参数

别名（Synonyms）	Dickkopf-1;DKK-1;SK Protein; DKK1; dkk1; dkk-1
表达区间及表达系统（Source）	Human DKK1 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Thr32-His266.[Accession \| O94907]
分子量大小（Molecular Weight）	The protein has a predicted MW of 26.87 kDa. Due to glycosylation, the protein migrates to 42-52 kDa based on Tris-Bis PAGE result.
内毒素（Endotoxin）	< 1.0 EU/μg by the LAL method.
纯度（Purity）	> 95% as determined by Tris-Bis PAGE and HPLC
生物活性（Biological Activity）	ELISA Data: Immobilized Human DKK1, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-DKK1 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA.
制剂（Formulation）	Lyophilized from 0.22μm filtered solution in 20mM PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
外观（Physical Appearance）	白色冻干粉