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当前位置:仪器网>产品中心> 翌圣生物科技(上海)股份有限公司>细胞因子>白介素>Recombinant Human IL-5 Protein, His-Fc tag
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Recombinant Human IL-5 Protein, His-Fc tag

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详细介绍

 

Interleukin 5 (IL-5) is a member of the hematopoietic Th2 cytokine family and consists of 115 amino acids. Unlike other members of the cytokine family (IL-3 and GM-CSF), this glycoprotein is activated as a homologous dimer. IL-5 is secreted by Th2 cells and mast cells. Its biological activity on B cells and other cell types suggests that IL-5 is functionally important for Th2 cell activity. By binding to its receptor, IL-5 stimulates B cell growth and enhances immunoglobulin secretion. It is also a key factor in the activation of eosinophils. IL-5 has been associated with a variety of diseases, including allergic rhinitis and asthma, with substantial increases seen in circulating tissue, tracheal tissue, and a decrease in sputum eosinophils.

 

性能参数

Synonyms

TRF,Interleukin-5

Uniprot No.

P05113-1

Source

Recombinant Human IL-5 Protein is expressed from HEK293 Cells with His tag at the N-terminal and Fc tag at the C-terminal. It contains Ile20-Ser134.

Molecular Weight

The protein has a predicted MW of  45.33 kDa.

Purity

> 95% as determined by SDS-PAGE.

Endotoxin

<0.1 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 ug/mL.

 

储存条件

The product should be stored at -25~-15℃ for 1 year from date of receipt.

2-7 days, 2 ~8 °C under sterile conditions after reconstitution.

3 months, -25~-15℃ under sterile conditions after reconstitution.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

注意事项

1.Please operate with lab coats and disposable gloves,for your safety.

2.This product is for research use only.

 

产品数据

 

Ver. CN20230411

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