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| 产品编号 | MAV102 |
|---|---|
| 产品名称 | Recombinant Human anti-COVID-19/SARS-CoV-2 S1 RBD Monoclonal Antibody |
| 抗体亚型 | IgG1 |
| 克隆号 | 7H6 |
| 规格与价格 | 100ul/￥2,300; 500ul/￥6,500; 1000ul/￥11,000 |
| 产品别称 | SARS-CoV-2 RBD antibody, 2019-nCoV, Coronavirus |
| 规格 | 100ul/￥2,300 |
| 物种 | COVID-19 |
| 宿主 | Human |
| 产品应用 | ELISA, Colloidal Gold, POCT, Neutralizaiton , Standard Positive Control |
| 内毒素水平 | <0.1EU/ug determided by LAL method. |
| 交叉反应 | React with SARS-CoV-2(COVID-19) S1-RBD protein. Do not react with other SARS-CoV-2 subunits. |
| 缓冲体系 | 0.01M PBS, pH 7.4 |
| 免疫原 | Native virus |
| 产品背景 | A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) recently emerged and is rapidly spreading in humans, causing COVID-19. A key to tackling this pandemic is to understand the receptor recognition mechanism of the virus, which regulates its infectivity, pathogenesis and host range. SARS-CoV-2 and SARS-CoV recognize the same receptor—angiotensin-converting enzyme 2 (ACE2)—in humans. Researchers determined the crystal structure of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 (engineered to facilitate crystallization) in complex with ACE2. In comparison with the SARS-CoV RBD, an ACE2-binding ridge in SARS-CoV-2 RBD has a more compact conformation; moreover, several residue changes in the SARS-CoV-2 RBD stabilize two virus-binding hotspots at the RBD–ACE2 interface. These structural features of SARS-CoV-2 RBD increase its ACE2-binding affinity. Additionally, we show that RaTG13, a bat coronavirus that is closely related to SARS-CoV-2, also uses human ACE2 as its receptor. |
| 保存条件 | This product can be stored at 2℃-8℃ for one month. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| 备注 | This product is used for research use only. Not for human or diagnostic use. |
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科研用途
科研
核酸提取
抗原制备，免疫实验
蛋白PEG修饰服务 卡梅德生物多年以来致力于重组蛋白表达，抗体制备研究，积累了丰富的技术经验。卡梅德生物能够提供多种方式的蛋白质修饰服务，包括荧光标记，PEG修饰以及磁珠偶联等服务。
ELISA, Colloidal Gold, POCT, Native Virus Detection, WB
ELISA, Colloidal Gold, POCT, Native Virus Detection, WB
ELISA
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