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解决方案
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运用ITC表征蛋白质的交互作用
发布:沃特世科技(上海)有限公司(TA)浏览次数:682When two proteins interact and bind, conformational changes in the proteins, and rearrangement of the solvent in the vicinity of the binding site, result in the absorption or generation of heat. Quantification of this reaction heat by ITC provides a complete thermodynamic description of the binding interaction, the stoichiometry of binding, and the association constant; in addition, if structural information is available, the contributions of specific amino acids mediating the binding event can be identified and their thermodynamic contributions quantified. Affinity 等温滴定微量热仪
2016-04-01相关仪器 -
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