Anti-RhoA 抗体说明书

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【导读】Anti-RhoA抗体说明书 Anti-RhoA抗体说明书 CatalogNumber:Rs-1180RQuantitysize:0.1ml（dilutewithpH7.4...

Anti-RhoA抗体说明书

CatalogNumber:Rs-1180RQuantitysize:0.1ml（dilutewithpH7.40.01MPBSorantibodydiluent）Background:ThisgeneencodesamemberoftheRhofamilyofsmallGTPases,whichcyclebetweeninactiveGDP-boundandactiveGTP-boundstatesandfunctionasmolecularswitchesinsignaltransductioncascades.Rhoproteinspromotereorganizationoftheactincytoskeletonandregulatecellshape,attachment,andmotility.TheproteinencodedbythisgeneisprenylatedatitsC-terminus,andlocalizestothecytoplasmandplasmamembrane.Itisthoughttobeimportantincelllocomotion.Overexpressionofthisgeneisassociatedwithtumorcellproliferationandmetastasis.Multiplealternativelysplicedvariants,encodingthesameprotein,havebeenidentified.Specificity:·anti-RhoAisarabbitmonoclonalantibodyunconjugated·specificforRhoAofhuman,mouse,rat,pig.·broadlyreactivewithmammalianspecies·epitopemappingneartheaminoterminusofRhoAofhuman,mouse,rat.·useforwesternblotting,elisa,immunoprecipitationandimmunohistochemistry·affinitychromatographypurification,purity:>95%·Isotype:IgG·molwt:21kDaApplication:·Westernblotting1:100-500·Immunohistochemistry1:100-500·ELISA1:500-1000·Optimalworkingdilutionsmustbedeterminedbytheenduser.Storage: Storeat–20ºCforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20ºC.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibody,theantibodyisstableforatleasttwoweeksat2-4ºC.ImportantNote: Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.

2004-07-13 09:31:27

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