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仪器网/ 行业应用/ 解决方案/ AN192 快速溶剂萃取HPLC分析人参.pdf

AN192 快速溶剂萃取HPLC分析人参.pdf

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INTRODUCTION
Ginseng, including Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius), are medicinal plants known worldwide. Notoginseng (Panax notoginseng), called Sanqi or Tianqi in China, is also a popular Chinese traditional medicine. Ginseng is believed
to improve the health of people recovering from illness, improve both mental and physical performance, decrease blood glucose, control blood pressure, and impart other benefcial effects. Clinical trials in China have demonstrated the effcacy of notoginseng in promoting blood circulation, removing blood stasis (including blood
clotting), relieving swel领, and alleviating pain.
1,2Asian ginseng, American ginseng, and notoginseng all belong to the Araliaceae family, and contain many similar compound classes, such as ginsenosides, amyloses, fatty acids, amino acids, and polypeptides. Ginsenosides are triterpene saponins, steroid-like
compounds thought to be the active components that impart the herbs medicinal properties. Ginsenosides are classifed as Ro, Ra, Rb1, Rb2, Rb3, Rc, Rd, Re, Rf, Rg1, Rg2, Rg3, Rh1, Rh2, Rh3, etc., depending on their Rf values (from small to large) by thin-layer chromatography (TLC). They can also be divided into three types based on their structures: Type A, 20(s)-protopanaxadiol (Figure
1A), Type B, 20(s)-protopanaxatriol (Figure 1B), and
Type C, oleanolic acid.3
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