Agilent 1290 Infinity II LC with ISET–Emulation of the Waters Acquity H-Class for Ternary Gradients

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2016-07-21 00:00 592阅读次数

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• Agilent 1290 Infinity II LC with ISET–Emulation of the Waters Acquity H-Class for Ternary Gradients

  Agilent Intelligent System Emulation Technology (ISET) within the Agilent 1290 Infinity II LC facilitates the transfer of methods from Agilent and non-Agilent HPLC and UHPLC systems. This Application Note shows how the 1290 Infinity II LC with ISET emulates the ternary gradient of a Waters Acquity H-Class system for the analysis of peptides. Over 97 % agreement is achieved using the 1290 Infinity II LC with ISET, in contrast to without ISET.[详细]

  2016-07-21 00:00

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• The Agilent Intelligent System Emulation Technology (ISET)

  Agilent 1290 Infinity II LC with ISET – Emulation of the Agilent 1100 Series LC Through Waters Empower Software Analysis of an Analgesic Mixture[详细]

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• Fast Determination of the Bitter and Clove-like Flavor in Beer with the Agilent 1290 Infinity II LC

  The Agilent 1290 Infinity II LC was used to determine the bitter compounds iso-alpha-acids and reduced iso-alpha-acids, and the clove-like phenolic flavor 4-vinylguaiacol in bottled beer.[详细]

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• HPLC to UHPLC Transfer of USP Method for Amlodipine Besylate Using the Agilent 1290 Infinity II LC

  Over the last decades, an increasing number of generic drug formulations have been released on the pharmaceutical market. These products are generally analyzed with compendia methods.[详细]

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• Impurity Testing of Fixed-Dose Combination Drugs Using the Agilent 1290 Infinity II HDR-DAD Impurity

  The Agilent 1290 Infinity II High Dynamic Range Diode Array Detection (HDR-DAD) Impurity Analyzer Solution combines the signals from two diode array detectors with different path length Max-Light cartridge cells to increase the linear dynamic UV-range. This solution can be used to detect and quantify main and trace compounds in a single run without exceeding the linear UV-range. Using one DAD with a 10-mm flow cell, typically two injections with different injection volumes are needed to determin[详细]

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• Agilent 1290 Infinity 液相色谱 系统对土壤样品中的痕量进行分析

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• Online 2D-LC Analysis of Complex N-Glycans in Biopharmaceuticals Using the Agilent 1290 Infinity 2D-LC Solution

  This Application Note presents different online 2D-LC concepts for the high-resolution analysis of complex N-linked glycans in erythropoietin (EPO) using the Agilent 1290 Infinity 2D-LC Solution with fluorescence detection. EPO has a complex glycosylation pattern with differently branched and charged glycans. A combination of hydrophilic interaction chromatography (HILIC) with weak anion exchange chromatography (WAX) enables highly orthogonal separation. Comprehensive 2D-LC analysis with HILIC in the first and WAX in the second dimension facilitates high-resolution 2D chromatography together with simultaneous charge profi领. In addition, multiple heart-cutting 2D-LC analysis, combining WAX and HILIC separation, provides a flexible alternative whereby the user can select multiple peaks to be analyzed in the second dimension and, moreover, run longer gradients.[详细]

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