Anti-Integrin αV+β3/CD51+CD61 抗体说明书

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【导读】Anti-IntegrinαV+β3/CD51+CD61抗体说明书 Anti-IntegrinαV+β3/CD51+CD61 抗体说明书 Cat.Number: Rs-...

Anti-IntegrinαV+β3/CD51+CD61抗体说明书

Anti-IntegrinαV+β3/CD51+CD61 抗体说明书

Cat.Number: Rs-1310R Quantitysize: 0.2ml （dilutewithpH7.4 0.01MPBSordiluentofantibody） Background: Integrinsareheterodimericproteinsmadeupofalphaandbetasubunits.Atleast18alphaand8betasubunitshavebeendescribedinmammals.Integrinfamilymembersaremembranereceptorsinvolvedincelladhesionandrecognitioninavarietyofprocessesincludingembryogenesis,hemostasis,tissuerepair,immuneresponseandmetatastaticdiffusionoftumourcells.ITAGVencodesintegrinalphachainV.Integrinsareheterodimericintegralmembraneproteinscomposedofanalphachainandabetachain.TheI-domaincontainingintegrinalphaVundergoespost-translationalcleavagetoyielddisulfide-linkedheavyandlightchains,thatcombinewithmultipleintegrinbetachainstoformdifferentintegrins.Amongtheknownassociatingbetachains（betachains1,3,5,6,and8;ITGB1,ITGB3,ITGB5,ITGB6,andITGB8）,eachcaninteractwithextracellularmatrixligands;thealphaVbeta3integrin,perhapsthemoststudiedofthese,isreferredtoastheVitronectinreceptor（VNR）.Inadditiontoadhesion,manyintegrinsareknowntofacilitatesignaltransduction.Anti-IntegrinαV+β3/CD51+CD61 抗体说明书 Specificity: ·anti-IntegrinαVβ3isamousemonoclonalantibodyunconjugated ·specificforIntegrinαVβ3proteinofhuman,mouse,rat,pigandrabbit · epitopemappingneartheaminoterminusofIntegrinαVβ3proteinofhuman,mouse,rat,pigandrabbit ·useforelisa,immunoprecipitationandimmunohistochemistry · ProteinGaffinitychromatographypurification,purity:>95%·Isotype:IgG Application: ·Westernblotting:1:100-500·Immunohistochemistry:1:100-500·ELISA:1:500-1000· Optimalworkingdilutionsmustbedeterminedbytheenduser. Storage: Storeat–20ºCforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20ºC.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4ºC. ImportantNote: Thisproductassuppliedis intendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.

Anti-IntegrinαV+β3/CD51+CD61 抗体说明书

2004-07-13 09:31:27

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