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Recombinant Human LRP-5 Protein, hFc Tag
- 品牌：翌圣生物
- 产地：
- 供应商报价：面议
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翌圣生物科技(上海)股份有限公司
更新时间：2024-12-24 09:03:45 -
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入驻年限第1年
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详细介绍
The LDL receptor-related proteins LRP-5 and LRP-6 constitute a distinct subgroup of the LDL receptor family. Both are widely expressed type I transmembrane proteins that function as Wnt co-receptors with Frizzled proteins in the beta-catenin signaling pathway. Both also play critical roles in gastrulation and skeletal patterning during development.LRP-5/6 associates with Wnt/Frizzled complexes, triggering phosphorylation of its intracellular PPPS motifs, binding of Axin, and propagation of beta -catenin signals.
产品性质
Synonyms
LRP-5; LRP-7; LR3; BMND1; BMND1OPTA1; EVR1; EVR4; HBM; LR3VBCH2; LRP5; LRP7; OPPG; OPS; OPTA1; VBCH2
Uniprot No.
O75197-1
Source
Recombinant Human LRP-5 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Glu644-Gln1263.
Molecular Weight
The protein has a predicted MW of 96.51 kDa. Due to glycosylation, the protein migrates to 100-115 kDa based on Tris-Bis PAGE result.
Purity
> 95% as determined by SDS-PAGE and HPLC.
Endotoxin
< 1.0 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
运输与保存方法
The products are shipped with dry ice and can be stored at -25~-15℃ for 1 year.
2-7 days, 2 ~ 8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
注意事项
- For your safety and health, please wear lab coats and disposable gloves for operation.
- For research use only!
产品数据
HB230208
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