Recombinant Cynomolgus IL-13 Protein,His Tag
Recombinant Cynomolgus IL-4 Protein,His Tag
Recombinant Cynomolgus IL-6 Protein,His Tag
Recombinant Cynomolgus IL-3 Protein,His Tag
Recombinant Cynomolgus IL-1 Beta/IL-1F2 Protein,His Tag
The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The EGFR subfamily of receptor tyrosine kinases comprises four members: EGFR, HER2 , HER3 and HER4 . Within the ECD, human EGFR shares 88% aa sequence identity with mouse and rat EGFR. EGFR binds a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, and epigen. EGFR signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis.
产品性质
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Synonyms |
ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2 |
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Uniprot No. |
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Source |
Recombinant Biotinylated Human EGFR/HER1 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Leu25-Ser645. |
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Molecular Weight |
The protein has a predicted MW of 71.5 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result. |
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Purity |
> 95% as determined by SDS-PAGE and HPLC |
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Activity |
SPR data: Biotinylated Human EGFR, His-Avi Tag captured on CM5 Chip via Anti-his antibody can bind Human EGF, No Tag with an affinity constant of 0.64 nM as determined in SPR assay. |
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Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
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Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
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Reconstitution |
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL` is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water. |
运输与保存方法
The products are shipped with ice pack and can be stored at -20℃ for 1 year.
2-7 days, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
注意事项
1.For your safety and health, please wear lab coats and disposable gloves for operation.
2.For research use only!
产品数据

HB221103
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