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仪器网>产品中心> 翌圣生物科技(上海)股份有限公司>重组蛋白1>CAR-T靶点蛋白>Recombinant Human CEACAM-1/CD66a (His Tag)

Recombinant Human CEACAM-1/CD66a (His Tag)

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翌圣生物 2026-04-29 10:23:22
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产品详情:

 

Carcinoembryonic antigen (CEA)-related cell adhesion molecule 1 (CEACAM-1; also BGP) is a 160 kDa member of the CEACAM branch of the CEA gene family of the immunoglobulin superfamily . There is no CEACAM-2 in human. The gene for human CEACAM-1 codes for a 526 amino acid (aa) type I transmembrane protein that contains a 34 aa signal sequence, a 394 aa extracellular domain (ECD), a 24 aa transmembrane segment, and a 74 aa cytoplasmic region. The ECD contains one N-terminal V-type Ig-like domain, followed by three C2-type Ig-like domains. It shows considerable glycosylation, including high mannose residues and (sialyl) LewisX. The cytoplasmic region shows one ITIM motif and a calmodulin binding site.  

 

产品性质

别名

BGP; BGP1; BGPI; CEACAM1; CD66a

Uniprot No.

P13688.1

表达区间及表达系统

Recombinant Human CEACAM-1/CD66a Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Gln35-Gly428.

分子量

Approximately 44.4 kDa. Due to glycosylation, the protein migrates to 68-115 kDa based on Tris-Bis PAGE result.

纯度

> 95% as determined by SDS-PAGE and HPLC.

活性

ELISA DataImmobilized Human CEACAM-1 at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CEACAM-1 Antibody, hFc Tag with the EC50 of 7.1ng/ml determined by ELISA.

内毒素

1.0 EU per 1μg of the protein by the LAL method.

制剂

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.

复溶

Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.

 

运输与保存方法

冰袋运输-20-80存,一年有效期

复溶后,-20 -80°C,在未开封状态下保存 3-6 个月复溶后,2-8°C 保存 2-7 天。

建议第一次使用时分装存,避免反复冻融

 

 注意事项

1. 避免反复冻融。

2. 为了您的安全和健康,请穿实验服并戴一次性手套操作。

3. 本产品仅作科研用途!

 

产品数据
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HB220810

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