Recombinant Rat Uteroglobin
Recombinant Rat CT-1
Recombinant Rat Tropic1808, His
Recombinant Mouse Uteroglobin
Recombinant Mouse FABP1
Bcl-2 is a member of a family of proteins that regulates outer mitochondrial membrane permeability. Bcl-2 is an anti-apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Bcl-2 is present on the outer mitochondrial membrane and is also found on other membranes in some cell types. Natural Bcl-2 contains a carboxyl-terminal mitochondria targeting sequence. Recombinant Bcl-2, missing the mitochondrial targeting sequence, maintains its ability to neutralize pro-apoptotic Bcl-2 family members. Neutralization by Bcl-2 appears to be through binding the BH3 region of pro-apoptotic Bcl-2 family members. This activity does not require the mitochondrial targeting sequence.
Product Properties
|
Synonyms |
PPP1R50 Protein |
|
Accession |
P10415 |
|
GeneID |
596 |
|
Source |
E.coli-derived Human Bcl-2, Ala2-Asp211. |
|
Molecular Weight |
Approximately 23.2 kDa. |
|
AA Sequence |
AHAGRTGYDN REIVMKYIHY KLSQRGYEWD AGDVGAAPPG AAPAPGIFSS QPGHTPHPAA SRDPVARTSP LQTPAAPGAA AGPALSPVPP VVHLTLRQAG DDFSRRYRRD FAEMSSQLHL TPFTARGRFA TVVEELFRDG VNWGRIVAFF EFGGVMCVES VNREMSPLVD NIALWMTEYL NRHLHTWIQD NGGWDAFVEL YGPSMRPLFD |
|
Tag |
None |
|
Physical Appearance |
Sterile liquid. |
|
Purity |
> 95% by SDS-PAGE and HPLC analyses. |
|
Biological Activity |
Test in Process. |
|
Endotoxin |
Less than 0.1 EU/µg of rHuBcl-2 as determined by LAL method. |
|
Formulation |
0.2 µm filtered concentrated solution in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 1 mM DTT, 30% Glycerol, with Tween-80. |
|
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only!
HB220301
报价：面议
已咨询56次重组蛋白1
报价：面议
已咨询19次其他重组蛋白
报价：面议
已咨询19次其他重组蛋白
报价：面议
已咨询60次生物医药1
营业执照已审核
分享
收藏
沪公网安备 31011502008050号