仪器网(yiqi.com)欢迎您!

| 注册 登录
网站首页-资讯-专题- 微头条-话题-产品- 品牌库-搜索-供应商- 展会-招标-采购- 社区-知识-技术-资料库-方案-产品库- 视频

产品中心

当前位置:仪器网>产品中心> 翌圣生物科技(上海)股份有限公司>细胞因子>成纤维细胞生长因子>Recombinant Human FGF-16
收藏  

Recombinant Human FGF-16

立即扫码咨询

联系方式:400-611-1883

联系我们时请说明在仪器网(www.yiqi.com)上看到的!

扫    码    分   享
为您推荐

详细介绍

Fibroblast growth factor-16 (FGF16) is a member of FGF9 subfamily. All FGF family members are heparin-binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. FGF-16 is most similar to FGF-9, sharing 73% aa sequence homology. Human FGF-16 shares 99% and 98.6% aa sequence identity with the mouse and rat FGF-16, respectively. FGF-16 binds to and activates FGF receptor 4. The expression pattern of FGF-16 and its effect on adipocyte proliferation suggest a role for this protein on the proliferation of embryonic brown adipose tissue. FGF16 belongs to the large FGF family, which plays key role in promoting mitosis and cell survival, and also involved in embryonic development, cell growth, tissue repair, morphogenesis, tumor growth, and invasion. Meanwhile, the expression of FGF-16 in the perinatal and postnatal heart and its functional significance in neonatal rat cardiac myocytes.

 

Product Properties

Synonyms

FGF16, FGF-16, fibroblast growth factor 16

Accession

O43320

GeneID

8823

Source

E.coli-derived human FGF-16 protein, Ala2-Arg207.

Molecular Weight

Approximately 23.6 kDa.

AA Sequence

AEVGGVFASL DWDLHGFSSS LGNVPLADSP GFLNERLGQI EGKLQRGSPT DFAHLKGILR RRQLYCRTGF HLEIFPNGTV HGTRHDHSRF GILEFISLAV GLISIRGVDS GLYLGMNERG ELYGSKKLTR ECVFREQFEE NWYNTYASTL YKHSDSERQY YVALNKDGSP REGYRTKRHQ KFTHFLPRPV DPSKLPSMSR DLFHYR

Tag

None

Physical Appearance

Sterile Colorless liquid.

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 × 106 IU/mg. Fully biologically active when compared to standard.

Endotoxin

0.1 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris-HCl, 1 M NaCl, pH 9.0, with 0.02 % Tween-20, 10 % Glycerol.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20 to -70℃ for 6 months.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1. Avoid repeated freeze-thaw cycles.

2. For your safety and health, please wear lab coats and disposable gloves for operation.

3. For research use only!

 

HB220303

 

厂商推荐产品

在线留言

换一张?
取消