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Recombinant Human Noggin Protein, His Tag

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详细介绍

Noggin is a bone morphogenetic protein (BMP) antagonist expressed in Spemann's organizer. It inhibits TGF-β family ligands and preventing them from binding to their corresponding receptors.

 

性能参数

Synonyms

NOG, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1

Uniprot No.

Q13253

Source

HEK293 cells -derived human Noggin protein, Gln28-Cys232, with a His tag at the C-terminal

Molecular Weight

The protein migrates as 30 KDa under reducing (R) condition (SDS-PAGE) .

 Activity

Measured by its ability to bind BMP2 with Elisa method .

Optimal concentrations should be determined by each laboratory for each application

Purity

> 95% as determined by SDS-PAGE.

Endotoxin

<1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.

 

储存条件

The product should be stored at -85~-65℃ for 1 year from date of receipt.

 

注意事项

1.Please operate with lab coats and disposable gloves,for your safety.

2.This product is for research use only.

 

产品数据

 

Ver. CN20230508

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