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Biotinylated Human NKG2D/CD314 Protein, His-Avi Tag
- 品牌:翌圣生物
- 产地:
- 供应商报价:面议
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翌圣生物科技(上海)股份有限公司
更新时间:2024-12-24 09:03:45
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入驻年限第1年
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详细介绍
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. Human NKG2D is expressed on CD8+ alpha beta T cells, gamma δ T cells, NK cells and NKT cells. In mouse systems NKG2D also occurs on macrophages. Human ligands for NKG2D include MICA, MICB, and ULBP1, 2, and 3. Expression of NKG2D ligands occurs in epithelial cells, tumor cells and under conditions of stress or infection. NKG2D exists as a disulfide-linked homodimer that delivers an activating signal upon ligand binding. NKG2D has been implicated in anti-tumor surveillance and the immune response against viral infection.
产品性质
Synonyms
CD314; D12S2489E; KLR; NKG2-D; NKG2D
Uniprot No.
P26718
Source
Recombinant Biotinylated Human NKG2D/CD314 Protein is expressed from HEK293 Cells with His tag and Avi tag at the N-terminal. It contains Phe78-Val216.
Molecular Weight
The protein has a predicted MW of 19.0 kDa. Due to glycosylation, the protein migrates to 36-40 kDa based on Tris-Bis PAGE result.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
> 95% as determined by SDS-PAGE and HPLC
Endotoxin
< 1.0 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge tubes before opening. Reconstituting to a concentration more than 100μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
运输与保存方法
The products are shipped with ice pack and can be stored at -20℃ for 1 year.
2-7 days, 2 to 8 °C under sterile conditions after reconstitution.
3 -6 months, -20 to -80°C under sterile conditions after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
注意事项
1.For your safety and health, please wear lab coats and disposable gloves for operation.
2.For research use only!
产品数据
HB230118
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