An in situ fiber-optic dissolution test of the glipizide
MR formulation was also evaluated using Delphian
Technology L.P.s Rainbow Dynamic Dissolution
MonitorTM (Ardsley, New York). The dissolution
was performed at 75 rpm speed using a similar apparatus
andmedium as described above for the glipizide
MRformulation. The data were collected every 30 min
up to 22 h using a fiber-optic probe set at 276nmwavelength.
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