艾普拜生物(apexbio)的研发团队近日在知名杂志《British Journal of Cancer》(BJC)上发表了一篇题为Plasma-based early screening and monitoring of EGFR mutations in NSCLC patients by a 3-color digital PCR assay的文章。这篇文章通过高灵敏的数字PCR技术对NSCLC患者血浆中的EGFR水平进行突变检测,并可同时检测EGFR基因第18-21外显子的39个突变,极大提高临床EGFR突变检测能力,尤其是当待测样本有限时,该方法可从少量样本中获得更多基因信息。该杂志影响因子5.791。(详情请见文末)
艾普拜生物(apexbio)的研发团队近日在知名杂志《British Journal of Cancer》(BJC)上发表了一篇题为Plasma-based early screening and monitoring of EGFR mutations in NSCLC patients by a 3-color digital PCR assay的文章。这篇文章通过高灵敏的数字PCR技术对NSCLC患者血浆中的EGFR水平进行突变检测,并可同时检测EGFR基因第18-21外显子的39个突变,极大提高临床EGFR突变检测能力,尤其是当待测样本有限时,该方法可从少量样本中获得更多基因信息。该杂志影响因子5.791。(详情请见文末)[详细]
TBI:
Microvascular Injury in Mild Traumatic Brain Injury Accelerates Alzheimer-like Pathogenesis in Mice
Lower limb:
DW14006 as a direct AMPK activator ameliorates diabetic peripheral neuropathy in mice
Lymph and blood vessels:
Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage
Ischemia model:
14-3-3ζ-c-Src-integrin-β3 complex is vital for platelet activation
Diabetes and BBB:
Aging exacerbates impairments of cerebral blood flow autoregulation and cogniti[详细]
近日ZG疾病预防控制ZX病毒病预防控制所朊病毒实验室,在Virologica Sinica杂志上发表“IP10, KC and M-CSF is Remarkably Increased in the Brains from the Various Strains of Experimental Mice Infected with Different Scrapie Agents”。该研究采用了Luminex、ELISA、IHC和RT-PCR等多种方法,发现IP10、KC和M-CSF转录及翻译水平在不同羊瘙痒症感染啮齿类动物模型大脑中其含量显著升高,且与小鼠的遗传背景无关。这项研究旨在探究炎症细胞因子和趋化因子与朊病毒疾病的相关性,这些数据使我们对朊病毒感染期间的炎症反应和朊病毒疾病的进展有了更好的了解。该杂志2020年影响因子3.242。(详情请见文末)[详细]
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