Diatoms are worldwide abundant unicellular microalgae (Fig.1). Their fossilized remains are the main component of diatomite, a mineral widely utilized in many differentindustries as an absorbent or additive. The chemical composition of the shells is critical for the properties of the final product. Therefore, there is a huge need to analyze the elemental distribution in the original diatoms.
Diatoms are worldwide abundant unicellular microalgae (Fig.1). Their fossilized remains are the main component of diatomite, a mineral widely utilized in many differentindustries as an absorbent or additive. The chemical composition of the shells is critical for the properties of the final product. Therefore, there is a huge need to analyze the elemental distribution in the original diatoms. [详细]
Red wine produced from the Malbec grape is increasing in popularity in the United States. However, the US is a relatively small producer of the wine compared to Argentina, where it is the most extensively planted grape variety in the country. With rising imports into the US from Argentina there are growing concerns relating to the validation of the geographical origin of this wine. [详细]
The development of a Time of Flight Secondary Ion Mass Spectrometer (TOF-SIMS) that can be
attached to a FIB-SEM instrument provides an analyzer that very well complements the standard EDS detector. However, contrary to EDS, it gives much better depth resolution, possibility of depth profiling as well as distinguishing isotopes. [详细]
Recombinant monoclonal antibodies (mAbs) have emerged as important therapeutic agents for the treatment of different diseases. This technology has been extended by the development of antibody drug conjugates (ADCs). [详细]
A preliminary assessment of environmental volatiles in water using static headspace analysis was performed using the Agilent 7697A Headspace Sampler, Agilent 7890B GC, and the Agilent 5977B GC/MSD system with high efficiency source (HES). The revolutionary design of the HES produces a higher ion currentyield for many compounds (greater sensitivity), which allows flexible approaches to sample analysis such as lowering detection limits, reducing sample size, speeding up analysis, and so forth.[详细]
The analytical requirements of the geological survey and mining industries are demanding in terms of high number of samples, number of elements, time/cost constraints and the difficult matrices. [详细]
Laser Ablation-ICP-MS (LA-ICP-MS) is used for the elemental analysis of solid samples and powders,including geological materials, ceramics, biological tissue and forensic samples.[详细]
This Application Note presents different online 2D-LC concepts for the high-resolution analysis of complex N-linked glycans in erythropoietin (EPO) using the Agilent 1290 Infinity 2D-LC Solution with fluorescence detection. EPO has a complex glycosylation pattern with differently branched and charged glycans. A combination of hydrophilic interaction chromatography (HILIC) with weak anion exchange chromatography (WAX) enables highly orthogonal separation. Comprehensive 2D-LC analysis with HILIC in the first and WAX in the second dimension facilitates high-resolution 2D chromatography together with simultaneous charge profi领. In addition, multiple heart-cutting 2D-LC analysis, combining WAX and HILIC separation, provides a flexible alternative whereby the user can select multiple peaks to be analyzed in the second dimension and, moreover, run longer gradients.[详细]
Elemental Analysis of Diatom Cell walls using a FIB-SEM-TOF-SIMS
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