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仪器网>产品中心> 翌圣生物科技(上海)股份有限公司>细胞因子2>其他生长因子1>Recombinant Human Proinsulin C-Peptide Analogue

Recombinant Human Proinsulin C-Peptide Analogue

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翌圣生物 2026-01-09 10:22:40
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产品详情:

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

 

Product Properties

Synonyms

Human Proinsulin C-Peptide Analogue, IDDM Protein, Human; IDDM1 Protein, Human

Accession

P01308

GeneID

3630

Source

E.coli-derived human Proinsulin C-Peptide Analogue protein,Arg55-Arg89

Molecular Weight

Approximately 3.6 kDa.

AA Sequence

RREAEDLQVG QVELGGGPGA GSLQPLALEG SLQKR

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 95 % by SDS-PAGE and HPLC analyses.

Biological Activity

Data Not Available.

Endotoxin

0.1 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.4.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1. Avoid repeated freeze-thaw cycles.

2. For your safety and health, please wear lab coats and disposable gloves for operation.

3. For research use only!

 

HB220210

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