Recombinant Exendin-4

Accession

P26349

GeneID

8554  

Source

E.coli-derived Exendin-4

Molecular Weight

Approximately 4.2 kDa, a single non-glycosylated polypeptide chain containing 39 amino acids.

AA Sequence

HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 96 % by SDS-PAGE and HPLC analyses.

Biological Activity

1. Regulates Glucose levels rapidly;
2. Reduces Insulin resistance;
3. Reduces Glucagon;
4. Reduces HbA1c;
5. Stimulates beta cell growth which stimulates insulin production.

Endotoxin

< 10 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.4.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.