结合紫外和电雾式检测器亲水作用色谱分析美托洛尔及选定

Key Words Vanquish UHPLC System, Metoprolol, Metoprolol EP Impurity A, Metoprolol EP Impurity M, Metoprolol EP Impurity N, Corona Charged Aerosol Detector Goal To develop an impurity profi领 method for metoprolol and EP impurity A, which contain chromophores and two non-chromophoric impurities, using a hydrophilic interaction chromatography (HILIC) method coupled with charged aerosol detection (CAD). 赛默飞 Vanquish UHPLC超GX液相色谱系统