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Gαz-GTP 小鼠单抗
- 品牌：NewEast Biosciences
- 型号/货号： 30微升/26908
- 产地：湖北 武汉
- 供应商报价：面议
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武汉费斯德生物科技有限公司
更新时间：2023-04-16 23:55:39 -
销售范围售全国
入驻年限第3年
营业执照已审核
- 同类产品活性单抗(23件)
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产品特点
- GTP酶是GTP/GDP结合蛋白。被细胞表面受体(GPCR)激活后, 它能调节下游效应器的功能。它可以结合GTP、水解GTP，因此在激活的GTP结合状态和非激活的GDP结合状态之间切换。它具有内在的GTP酶活性，可将GTP水解为GDP，从而使G蛋白失活。我们精心筛选的小鼠单克隆抗体能捕捉到与GTP结合的具有活性的GTP酶。它们已被用于通过免疫组织化学监测细胞和组织中 G 蛋白的活化和分布。
详细介绍
货号: 26908 规格: 30 µL 基因符号: Gnaz 描述: Anti-Gαz-GTP Mouse Monoclonal Antibody 背景介绍: Heterotrimeric G proteins are critical cellular signal transducers. Gαz represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gαz proteins are being explored. 免疫原: Recombinant full length protein of active Gαz 经过测试的应用: IP, IHC,IF 推荐稀释比:
IP: 1 µg for 1~2 mg total cellular proteins
IHC, IF: 1:50-1:250浓度: 1 mg/ml 宿主: Mouse 形式: Liquid 克隆性: Monoclonal 亚型: IgG 纯度: Purified from ascites 防腐剂: No 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol 种属反应性: Anti-Gαz-GTP monoclonal antibody recognizes active Gαz of vertebrates. 储存条件: Store at -20°C. Avoid repeated freezing and thawing 免疫沉淀/蛋白质印迹: 
Gαz activation assay. Purified Gαz proteins were loaded as a control (lanes 1) or immunoprecipitated after treated with GDP (lane 2) or GTPγS (lane 3). Immunoprecipitation was done with the anti-Gαz-GTP monoclonal antibody (Cat. No. 26908). Immunoblot was with an anti-Gαz polyclonal antibody.
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